The hope is that the technology will eventually produce gene editors that are more nimble and more powerful than those that have been honed over billions of years of evolution.

The following report is by The New York Times (excerpts):

New A.I. technology is generating blueprints for microscopic biological mechanisms that can edit your DNA, pointing to a future when scientists can battle illness and diseases with even greater precision and speed than they can today.

Described in a research paper published on Monday by a Berkeley, Calif., startup called Profluent, the technology is based on the same methods that drive ChatGPT, the online chatbot that launched the A.I. boom after its release in 2022. The company is expected to present the paper next month at the annual meeting of the American Society of Gene and Cell Therapy.

Much as ChatGPT learns to generate language by analyzing Wikipedia articles, books and chat logs, Profluent’s technology creates new gene editors after analyzing enormous amounts of biological data, including microscopic mechanisms that scientists already use to edit human DNA.

Previously, CRISPR methods used mechanisms found in nature — biological material gleaned from bacteria that allows these microscopic organisms to fight off germs.

“They have never existed on Earth,” said James Fraser, a professor and chair of the department of bioengineering and therapeutic sciences at the University of California, San Francisco, who has read Profluent’s research paper. “The system has learned from nature to create them, but they are new.”

The hope is that the technology will eventually produce gene editors that are more nimble and more powerful than those that have been honed over billions of years of evolution.

On Monday, Profluent also said that it had used one of these A.I.-generated gene editors to edit human DNA and that it was “open sourcing” this editor, called OpenCRISPR-1. That means it is allowing individuals, academic labs and companies to experiment with the technology for free.

A.I. researchers often open source the underlying software that drives their A.I. systems, because it allows others to build on their work and accelerate the development of new technologies. But it is less common for biological labs and pharmaceutical companies to open source inventions like OpenCRISPR-1.

Though Profluent is open sourcing the gene editors generated by its A.I. technology, it is not open sourcing the A.I. technology itself.

Profluent’s technology […] learns from sequences of amino acids and nucleic acids — the chemical compounds that define the microscopic biological mechanisms that scientists use to edit genes. Essentially, it analyzes the behavior of CRISPR gene editors pulled from nature and learns how to generate entirely new gene editors.

“These A.I. models learn from sequences — whether those are sequences of characters or words or computer code or amino acids,” said Profluent’s chief executive, Ali Madani, a researcher who previously worked in the A.I. lab at the software giant Salesforce.

Profluent has not yet put these synthetic gene editors through clinical trials, so it is not clear if they can match or exceed the performance of CRISPR. But this proof of concept shows that A.I. models can produce something capable of editing the human genome.

The hope, Dr. Urnov said, is that this could, in the long term, lead to a world where medicines and treatments are quickly tailored to individual people even faster than we can do today. “I dream of a world where we have CRISPR on demand within weeks,” he said.


AUTHOR COMMENTARY

The WinePress has a number of reports on CRISPR creations that so many mad scientists are using to play and toil about with life, and now these tech geeks are taking it even further by now having AI extend their reasoning and ambition to alter life further.

In 2022 I reported: “CRISPR Experiment Goes Wrong And Turns Fluffy Hamsters Into “Mutant Rage Monsters”.” CRISPR can do some serious damage and the after effects are still relatively unknown, and now that AI is being turned loose to manipulate CRISPR, God only knows what will come of it.

Thus were they defiled with their own works, and went a whoring with their own inventions.

Psalm 106:39

[7] Who goeth a warfare any time at his own charges? who planteth a vineyard, and eateth not of the fruit thereof? or who feedeth a flock, and eateth not of the milk of the flock? [8] Say I these things as a man? or saith not the law the same also? [9] For it is written in the law of Moses, Thou shalt not muzzle the mouth of the ox that treadeth out the corn. Doth God take care for oxen? [10] Or saith he it altogether for our sakes? For our sakes, no doubt, this is written: that he that ploweth should plow in hope; and that he that thresheth in hope should be partaker of his hope. (1 Corinthians 9:7-10).

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1 Comment

  • So, in Revelation 9:16-17 could those horses have anything to do with these mad scientists? I understand the book of Revelation is sealed until Jesus opens it and by that time the body of Christ will not be here on the earth but I’m just wondering if they have any connection.

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