The team of microbiologists and chemical engineers are continuing to innovate by formulating RNA vaccines, like the Pfizer and Moderna COVID-19 vaccines, into microneedle patches for future testing.

In a collaboration between the University of North Carolina Chapel Hill and Stanford University, scientists have developed a 3D-printed vaccine patch that can provide more protection than the standard vaccines currently in use.

According to an university release, the patch is directly applied to the skin, that is loaded with immune cells that vaccines target. The patches are laced with microneedles that dissolve into the skin.

3D Printed Microneedle Vaccine Patch
Scientists at the University of North Carolina at Chapel Hill and Stanford University use 3D printer to produce microneedle vaccine patch that dissolves into the skin to boost immunity. Courtesy: University of North Carolina at Chapel Hill

According to study published in the Proceedings of the National Academy of Sciences, the results with these patches tested on animals found that this patch was 10 times more effective, than that of a traditional syringe vaccine injected into the arm.

The study further demonstrated that the patch created a higher level of T-cell and antigen-specific antibody response, which was 50 times higher than a traditional injection under the skin.

‘That heightened immune response could lead to dose sparing, with a microneedle vaccine patch using a smaller dose to generate a similar immune response as a vaccine delivered with a needle and syringe,’ said the report.

In developing this technology, we hope to set the foundation for even more rapid global development of vaccines, at lower doses, in a pain- and anxiety-free manner.

Lead study author and entrepreneur in 3D print technology Joseph M. DeSimone, professor of translational medicine and chemical engineering at Stanford University and professor emeritus at UNC-Chapel Hill

These new patches can also be customized for different purposes, such as influenza, hepatitis, measles, and even for Covid-19.

The authors of the report postulate that these patches could increase vaccination rates, as their tech does not need to be stored and transported in very specific ways (the Pfizer and Moderna Covid vaccines for example).

According to some of the developers, adapting the needles for different vaccination needs presents some challenges. Replication of the needles during the molding process slows the development down, as the needles lose their sharpness with each use of the molds.

These issues, coupled with manufacturing challenges, have arguably held back the field of microneedles for vaccine delivery.

Our approach allows us to directly 3D print the microneedles which gives us lots of design latitude for making the best microneedles from a performance and cost point-of-view.

Lead study author Shaomin Tian, researcher in the Department of Microbiology and Immunology in the UNC School of Medicine

‘The team of microbiologists and chemical engineers are continuing to innovate by formulating RNA vaccines, like the Pfizer and Moderna COVID-19 vaccines, into microneedle patches for future testing,’ the release explained.

One of the biggest lessons we’ve learned during the pandemic is that innovation in science and technology can make or break a global response. Thankfully we have biotech and health care workers pushing the envelope for us all.

Joseph M. DeSimone

The WinePress has reported on some of the other Covid-19 vaccines that are currently being developed that stray away from the traditional syringe, such as aerosol/nasal spray vaccines or foods with mRNA technology modified in them.

Bill Gates has also been working on vaccine-patch technology, such as his Quantum Dot vaccine.

Storing Medical Records Below the Skin's Surface With ...
https://scitechdaily.com/storing-medical-records-below-the-skins-surface-with-quantum-dot-dye/

He recently told India that he will be building mRNA factories in time for the next pandemic.


AUTHOR COMMENTARY

We are getting closer and closer to the mark of the beast. We are not there yet – as I have explained in other reports some of the other needed steps to get there; but we can clearly see it forming. Only those who are willfully blind cannot see what is happening.

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[16] And he causeth all, both small and great, rich and poor, free and bond, to receive a mark in their right hand, or in their foreheads: [17] And that no man might buy or sell, save he that had the mark, or the name of the beast, or the number of his name. [18] Here is wisdom. Let him that hath understanding count the number of the beast: for it is the number of a man; and his number is Six hundred threescore and six.

Revelation 13:16-18

[7] Who goeth a warfare any time at his own charges? who planteth a vineyard, and eateth not of the fruit thereof? or who feedeth a flock, and eateth not of the milk of the flock? [8] Say I these things as a man? or saith not the law the same also? [9] For it is written in the law of Moses, Thou shalt not muzzle the mouth of the ox that treadeth out the corn. Doth God take care for oxen? [10] Or saith he it altogether for our sakes? For our sakes, no doubt, this is written: that he that ploweth should plow in hope; and that he that thresheth in hope should be partaker of his hope. (1 Corinthians 9:7-10).

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2 Comments

  • If this isn’t the road to the mark system, what is? So what should we do? See verse below.

    Luke 21:28 – And when these things begin to come to pass, then look up, and lift up your heads; for your redemption draweth nigh.

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